人 GNA11 (NM_002067) cDNA克隆

Accession: NM_002067
基因名称: GNA11
基因别名: HHC2; GNA-11; HYPOC2
基因描述: Homo sapiens guanine nucleotide binding protein (G protein), alpha 11 (Gq class) (GNA11), mRNA.
种属: Human
CDS区长度: 1080 (查看编码区序列)
翻译后氨基酸长度: 359 (查看氨基酸序列)
产品编号 产品名称 载体 规格 价格
G100352 人 GNA11 (NM_002067) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene belongs to the family of guanine nucleotide-binding proteins (G proteins), which function as modulators or transducers in various transmembrane signaling systems. G proteins are composed of 3 units: alpha, beta and gamma. This gene encodes one of the alpha subunits (subunit alpha-11). Mutations in this gene have been associated with hypocalciuric hypercalcemia type II (HHC2) and hypocalcemia dominant 2 (HYPOC2). Patients with HHC2 and HYPOC2 exhibit decreased or increased sensitivity, respectively, to changes in extracellular calcium concentrations. [provided by RefSeq, Dec 2013]