人 TDP2 (NM_016614) cDNA克隆

Accession: NM_016614
基因名称: TDP2
基因别名: EAP2; AD022; EAPII; TTRAP; hTDP2; dJ30M3.3; RP1-30M3.3
基因描述: Homo sapiens tyrosyl-DNA phosphodiesterase 2 (TDP2), mRNA.
种属: Human
CDS区长度: 1089 (查看编码区序列)
翻译后氨基酸长度: 362 (查看氨基酸序列)
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G101413 人 TDP2 (NM_016614) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of a superfamily of divalent cation-dependent phosphodiesterases. The encoded protein associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor associated factors (TRAFs), and inhibits nuclear factor-kappa-B activation. This protein has sequence and structural similarities with APE1 endonuclease, which is involved in both DNA repair and the activation of transcription factors. [provided by RefSeq, Jul 2008]