人 ACTR1A (NM_005736) cDNA克隆

Accession: NM_005736
基因名称: ACTR1A
基因别名: ARP1; CTRN1
基因描述: Homo sapiens ARP1 actin-related protein 1 homolog A, centractin alpha (yeast) (ACTR1A), mRNA.
种属: Human
CDS区长度: 1131 (查看编码区序列)
翻译后氨基酸长度: 376 (查看氨基酸序列)
产品编号 产品名称 载体 规格 价格
G101486 人 ACTR1A (NM_005736) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60% identical at the amino acid level to conventional actin. [provided by RefSeq, Jul 2008]