人 MRPL12 (NM_002949) cDNA克隆

Accession: NM_002949
基因名称: MRPL12
基因别名: 5c5-2; L12mt; MRPL7; RPML12; MRPL7/L12; MRP-L31/34
基因描述: Homo sapiens mitochondrial ribosomal protein L12 (MRPL12), mRNA.
种属: Human
CDS区长度: 597 (查看编码区序列)
翻译后氨基酸长度: 198 (查看氨基酸序列)
产品编号 产品名称 载体 规格 价格
G103377 人 MRPL12 (NM_002949) cDNA克隆 pDONR223 2ug质粒 点击询价

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein which forms homodimers. In prokaryotic ribosomes, two L7/L12 dimers and one L10 protein form the L8 protein complex. [provided by RefSeq, Jul 2008]