人 DAO (NM_001917) cDNA克隆

Accession: NM_001917
基因名称: DAO
基因别名: DAAO; OXDA; DAMOX
基因描述: Homo sapiens D-amino-acid oxidase (DAO), mRNA.
种属: Human
CDS区长度: 1044 (查看编码区序列)
翻译后氨基酸长度: 347 (查看氨基酸序列)
产品编号 产品名称 载体 规格 价格
G106070 人 DAO (NM_001917) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes the peroxisomal enzyme D-amino acid oxidase. The enzyme is a flavoprotein which uses flavin adenine dinucleotide (FAD) as its prosthetic group. Its substrates include a wide variety of D-amino acids, but it is inactive on the naturally occurring L-amino acids. Its biological function is not known; it may act as a detoxifying agent which removes D-amino acids that accumulate during aging. In mice, it degrades D-serine, a co-agonist of the NMDA receptor. This gene may play a role in the pathophysiology of schizophrenia. [provided by RefSeq, Jul 2008]