人 NFKBIE (NM_004556) cDNA克隆

Accession: NM_004556
基因名称: NFKBIE
基因别名: IKBE
基因描述: Homo sapiens nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon (NFKBIE), mRNA.
种属: Human
CDS区长度: 1503 (查看编码区序列)
翻译后氨基酸长度: 500 (查看氨基酸序列)
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G106180 人 NFKBIE (NM_004556) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene binds to components of NF-kappa-B, trapping the complex in the cytoplasm and preventing it from activating genes in the nucleus. Phosphorylation of the encoded protein targets it for destruction by the ubiquitin pathway, which activates NF-kappa-B by making it available to translocate to the nucleus. [provided by RefSeq, Sep 2011]