人 VAC14 (NM_018052) cDNA克隆

基本信息

Accession: NM_018052
基因名称: VAC14
基因别名: TRX; TAX1BP2; ArPIKfyve
基因描述: Homo sapiens Vac14 homolog (S. cerevisiae) (VAC14), mRNA.
种属: Human
CDS区长度: 2349 (查看编码区序列)
翻译后氨基酸长度: 782 (查看氨基酸序列)

订购信息

产品编号 产品名称 载体 规格 价格
G106957 人 VAC14 (NM_018052) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

基因简介

The content of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) in endosomal membranes changes dynamically with fission and fusion events that generate or absorb intracellular transport vesicles. VAC14 is a component of a trimolecular complex that tightly regulates the level of PtdIns(3,5)P2. Other components of this complex are the PtdIns(3,5)P2-synthesizing enzyme PIKFYVE (MIM 609414) and the PtdIns(3,5)P2 phosphatase FIG4 (MIM 609390). VAC14 functions as an activator of PIKFYVE (Sbrissa et al., 2007 [PubMed 17556371]).[supplied by OMIM, Feb 2010]

相关产品