人 F11R (NM_016946) cDNA克隆

Accession: NM_016946
基因名称: F11R
基因别名: JAM; KAT; JAM1; JAMA; JCAM; CD321; PAM-1
基因描述: Homo sapiens F11 receptor (F11R), mRNA.
种属: Human
CDS区长度: 900 (查看编码区序列)
翻译后氨基酸长度: 299 (查看氨基酸序列)
产品编号 产品名称 载体 规格 价格
G109290 人 F11R (NM_016946) cDNA克隆 pDONR223 2ug质粒 点击询价

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established. [provided by RefSeq, Jul 2008]