人 GALNT6 (NM_007210) cDNA克隆

Accession: NM_007210
基因名称: GALNT6
基因别名: GalNAcT6; GALNAC-T6
基因描述: Homo sapiens UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6) (GALNT6), mRNA.
种属: Human
CDS区长度: 1869 (查看编码区序列)
翻译后氨基酸长度: 622 (查看氨基酸序列)
产品编号 产品名称 载体 规格 价格
G112476 人 GALNT6 (NM_007210) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. The encoded protein is capable of glycosylating fibronectin peptide in vitro and is expressed in a fibroblast cell line, indicating that it may be involved in the synthesis of oncofetal fibronectin. [provided by RefSeq, Jul 2008]