人 BAK1 (NM_001188) cDNA克隆

Accession: NM_001188
基因名称: BAK1
基因别名: BAK; CDN1; BCL2L7; BAK-LIKE
基因描述: Homo sapiens BCL2-antagonist/killer 1 (BAK1), mRNA.
种属: Human
CDS区长度: 636 (查看编码区序列)
翻译后氨基酸长度: 211 (查看氨基酸序列)
产品编号 产品名称 载体 规格 价格
G113231 人 BAK1 (NM_001188) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. [provided by RefSeq, Jul 2008]