人 APPL1 (NM_012096) cDNA克隆

Accession: NM_012096
基因名称: APPL1
基因别名: APPL; DIP13alpha
基因描述: Homo sapiens adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 (APPL1), mRNA.
种属: Human
CDS区长度: 2130 (查看编码区序列)
翻译后氨基酸长度: 709 (查看氨基酸序列)
产品编号 产品名称 载体 规格 价格
G113651 人 APPL1 (NM_012096) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus. [provided by RefSeq, Jul 2008]