人 HAVCR2 (NM_032782) cDNA克隆

Accession: NM_032782
基因名称: HAVCR2
基因别名: TIM3; KIM-3; TIMD3; Tim-3; TIMD-3; HAVcr-2
基因描述: Homo sapiens hepatitis A virus cellular receptor 2 (HAVCR2), mRNA.
种属: Human
CDS区长度: 906 (查看编码区序列)
翻译后氨基酸长度: 301 (查看氨基酸序列)
产品编号 产品名称 载体 规格 价格
G117293 人 HAVCR2 (NM_032782) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. [provided by RefSeq, Sep 2011]