人 ATP1A2 (NM_000702) cDNA克隆

Accession: NM_000702
基因名称: ATP1A2
基因别名: FHM2; MHP2
基因描述: Homo sapiens ATPase, Na+/K+ transporting, alpha 2 polypeptide (ATP1A2), mRNA.
种属: Human
CDS区长度: 3063 (查看编码区序列)
翻译后氨基酸长度: 1020 (查看氨基酸序列)
产品编号 产品名称 载体 规格 价格
G119346 人 ATP1A2 (NM_000702) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 2 subunit. Mutations in this gene result in familial basilar or hemiplegic migraines, and in a rare syndrome known as alternating hemiplegia of childhood. [provided by RefSeq, Oct 2008]