人 IL23A (NM_016584) cDNA克隆

Accession: NM_016584
基因名称: IL23A
基因别名: P19; SGRF; IL-23; IL-23A; IL23P19
基因描述: Homo sapiens interleukin 23, alpha subunit p19 (IL23A), mRNA.
种属: Human
CDS区长度: 570 (查看编码区序列)
翻译后氨基酸长度: 189 (查看氨基酸序列)
产品编号 产品名称 载体 规格 价格
G120281 人 IL23A (NM_016584) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a subunit of the heterodimeric cytokine interleukin 23 (IL23). IL23 is composed of this protein and the p40 subunit of interleukin 12 (IL12B). The receptor of IL23 is formed by the beta 1 subunit of IL12 (IL12RB1) and an IL23 specific subunit, IL23R. Both IL23 and IL12 can activate the transcription activator STAT4, and stimulate the production of interferon-gamma (IFNG). In contrast to IL12, which acts mainly on naive CD4(+) T cells, IL23 preferentially acts on memory CD4(+) T cells. [provided by RefSeq, Jul 2008]