人 HAND2 (NM_021973) cDNA克隆

Accession: NM_021973
基因名称: HAND2
基因别名: Hed; dHand; DHAND2; Thing2; bHLHa26
基因描述: Homo sapiens heart and neural crest derivatives expressed 2 (HAND2), mRNA.
种属: Human
CDS区长度: 654 (查看编码区序列)
翻译后氨基酸长度: 217 (查看氨基酸序列)
产品编号 产品名称 载体 规格 价格
G121820 人 HAND2 (NM_021973) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, this transcription factor plays an important role in limb and branchial arch development. [provided by RefSeq, Jul 2008]