人 IBTK (NM_015525) cDNA克隆

Accession: NM_015525
基因名称: IBTK
基因别名: BTKI; BTBD26; RP1-93K22.1
基因描述: Homo sapiens inhibitor of Bruton agammaglobulinemia tyrosine kinase (IBTK), mRNA.
种属: Human
CDS区长度: 4062 (查看编码区序列)
翻译后氨基酸长度: 1353 (查看氨基酸序列)
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G122461 人 IBTK (NM_015525) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene binds to Bruton's tyrosine kinase (BTK) and downregulates BTK's kinase activity. In addition, the encoded protein disrupts BTK-mediated calcium mobilization and negatively regulates the activation of nuclear factor-kappa-B-driven transcription. [provided by RefSeq, Jul 2008]