人 REL (NM_002908) cDNA克隆

Accession: NM_002908
基因名称: REL
基因别名: C-Rel
基因描述: Homo sapiens v-rel avian reticuloendotheliosis viral oncogene homolog (REL), mRNA.
种属: Human
CDS区长度: 1860 (查看编码区序列)
翻译后氨基酸长度: 619 (查看氨基酸序列)
产品编号 产品名称 载体 规格 价格
G123208 人 REL (NM_002908) cDNA克隆 pDONR223 2ug质粒 点击询价

The REL gene encodes c-Rel, a transcription factor that is a member of the Rel/NFKB family, which also includes RELA (MIM 164014), RELB (604758), NFKB1 (MIM 164011), and NFKB2 (MIM 164012). These proteins are related through a highly conserved N-terminal region termed the 'Rel domain,' which is responsible for DNA binding, dimerization, nuclear localization, and binding to the NFKB inhibitor (MIM 164008) (Belguise and Sonenshein, 2007 [PubMed 18037997]).[supplied by OMIM, May 2008]