人 AKAP5 (NM_004857) cDNA克隆

Accession: NM_004857
基因名称: AKAP5
基因别名: H21; AKAP75; AKAP79
基因描述: Homo sapiens A kinase (PRKA) anchor protein 5 (AKAP5), mRNA.
种属: Human
CDS区长度: 1284 (查看编码区序列)
翻译后氨基酸长度: 427 (查看氨基酸序列)
产品编号 产品名称 载体 规格 价格
G125184 人 AKAP5 (NM_004857) cDNA克隆 pDONR223 2ug质粒 点击询价

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein binds to the RII-beta regulatory subunit of PKA, and also to protein kinase C and the phosphatase calcineurin. It is predominantly expressed in cerebral cortex and may anchor the PKA protein at postsynaptic densities (PSD) and be involved in the regulation of postsynaptic events. It is also expressed in T lymphocytes and may function to inhibit interleukin-2 transcription by disrupting calcineurin-dependent dephosphorylation of NFAT. [provided by RefSeq, Jul 2008]