人 AASS (NM_005763) cDNA克隆

Accession: NM_005763
基因名称: AASS
基因别名: LKRSDH; LORSDH; LKR/SDH
基因描述: Homo sapiens aminoadipate-semialdehyde synthase (AASS), mRNA.
种属: Human
CDS区长度: 2781 (查看编码区序列)
翻译后氨基酸长度: 926 (查看氨基酸序列)
产品编号 产品名称 载体 规格 价格
G126468 人 AASS (NM_005763) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a bifunctional enzyme that catalyzes the first two steps in the mammalian lysine degradation pathway. The N-terminal and the C-terminal portions of this enzyme contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively, resulting in the conversion of lysine to alpha-aminoadipic semialdehyde. Mutations in this gene are associated with familial hyperlysinemia. [provided by RefSeq, Jul 2008]