人 ADAMTS8 (NM_007037) cDNA克隆

Accession: NM_007037
基因名称: ADAMTS8
基因别名: METH2; ADAM-TS8
基因描述: Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif, 8 (ADAMTS8), mRNA.
种属: Human
CDS区长度: 2670 (查看编码区序列)
翻译后氨基酸长度: 889 (查看氨基酸序列)
产品编号 产品名称 载体 规格 价格
G127760 人 ADAMTS8 (NM_007037) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains two C-terminal TS motifs, and disrupts angiogenesis in vivo. A number of disorders have been mapped in the vicinity of this gene, most notably lung neoplasms. [provided by RefSeq, Jul 2008]