人 AGTR2 (NM_000686) cDNA克隆

Accession: NM_000686
基因名称: AGTR2
基因别名: AT2; ATGR2; MRX88
基因描述: Homo sapiens angiotensin II receptor, type 2 (AGTR2), mRNA.
种属: Human
CDS区长度: 1092 (查看编码区序列)
翻译后氨基酸长度: 363 (查看氨基酸序列)
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G134840 人 AGTR2 (NM_000686) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene belongs to the G-protein coupled receptor 1 family, and functions as a receptor for angiotensin II. It is an intergral membrane protein that is highly expressed in fetus, but scantily in adult tissues, except brain, adrenal medulla, and atretic ovary. This receptor has been shown to mediate programmed cell death and this apoptotic function may play an important role in developmental biology and pathophysiology. Mutations in this gene are been associated with X-linked mental retardation. [provided by RefSeq, Jan 2010]