人 IBSP (NM_004967) cDNA克隆

Accession: NM_004967
基因名称: IBSP
基因别名: BSP; BNSP; SP-II; BSP-II
基因描述: Homo sapiens integrin-binding sialoprotein (IBSP), mRNA.
种属: Human
CDS区长度: 954 (查看编码区序列)
翻译后氨基酸长度: 317 (查看氨基酸序列)
产品编号 产品名称 载体 规格 价格
G149642 人 IBSP (NM_004967) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene is a major structural protein of the bone matrix. It constitutes approximately 12% of the noncollagenous proteins in human bone and is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor. [provided by RefSeq, Jul 2008]