人 ARHGDIB (NM_001175) cDNA克隆

Accession: NM_001175
基因名称: ARHGDIB
基因别名: D4; GDIA2; GDID4; LYGDI; Ly-GDI; RAP1GN1; RhoGDI2
基因描述: Homo sapiens Rho GDP dissociation inhibitor (GDI) beta (ARHGDIB), mRNA.
种属: Human
CDS区长度: 606 (查看编码区序列)
翻译后氨基酸长度: 201 (查看氨基酸序列)
产品编号 产品名称 载体 规格 价格
G151886 人 ARHGDIB (NM_001175) cDNA克隆 pDONR223 2ug质粒 点击询价

Members of the Rho (or ARH) protein family (see MIM 165390) and other Ras-related small GTP-binding proteins (see MIM 179520) are involved in diverse cellular events, including cell signaling, proliferation, cytoskeletal organization, and secretion. The GTP-binding proteins are active only in the GTP-bound state. At least 3 classes of proteins tightly regulate cycling between the GTP-bound and GDP-bound states: GTPase-activating proteins (GAPs), guanine nucleotide-releasing factors (GRFs), and GDP-dissociation inhibitors (GDIs). The GDIs, including ARHGDIB, decrease the rate of GDP dissociation from Ras-like GTPases (summary by Scherle et al., 1993 [PubMed 8356058]).[supplied by OMIM, Dec 2010]