heterodimerizes and antagonizes the activity of prosurvival proteins (Bcl-2, Bcl-XL) and promotes apoptosis; provokes mitochondrial defects and cell death of ventricular myocytes during hypoxia [RGD, Feb 2006]
heterodimerizes and antagonizes the activity of prosurvival proteins (Bcl-2, Bcl-XL) and promotes apoptosis; provokes mitochondrial defects and cell death of ventricular myocytes during hypoxia [RGD, Feb 2006]