人 ECEL1 (NM_004826) cDNA克隆

Accession: NM_004826
基因名称: ECEL1
基因别名: XCE; DA5D; DINE; ECEX
基因描述: Homo sapiens endothelin converting enzyme-like 1 (ECEL1), mRNA.
种属: Human
CDS区长度: 2328 (查看编码区序列)
翻译后氨基酸长度: 775 (查看氨基酸序列)
产品编号 产品名称 载体 规格 价格
G167664 人 ECEL1 (NM_004826) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the M13 family of endopeptidases. In general, M13 family members are zinc-containing type II integral-membrane proteins that are important regulators of neuropeptide and peptide hormone activity. This gene is expressed specifically in the central nervous system and its protein localizes predominately to the endoplasmic reticulum or, in trace amounts, to the cell surface. Disruption of this gene in mouse embryonic stem cells results in neonatal lethality due to respiratory failure shortly after birth. Based on the specific expression of this gene and the phenotype of the gene deficiency in mouse embryos, it is suggested that this protein plays a critical role in neural regulation of the respiratory system. This gene has multiple pseudogenes. [provided by RefSeq, Jul 2008]