小鼠 Bmpr2 (NM_007561) cDNA克隆

Accession: NM_007561
基因名称: Bmpr2
基因别名: BMP-2; BRK-3; BMPR-2; BMPRII; BMPR-II; Gm20272; AL117858; AW546137; BB189135; 2610024H22Rik
基因描述: Mus musculus bone morphogenetic protein receptor, type II (serine/threonine kinase) (Bmpr2), mRNA.
种属: Mouse
CDS区长度: 3117 (查看编码区序列)
翻译后氨基酸长度: 1038 (查看氨基酸序列)
产品编号 产品名称 载体 规格 价格
G168368 小鼠 Bmpr2 (NM_007561) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a serine/threonine kinase that functions as a receptor for bone morphogenetic proteins (BMPs). The encoded protein is a type II receptor that binds extracellular BMPs and forms a complex of two type II and two type I receptors at the cell membrane. This complex signals downstream to activate SMAD transcriptional regulators. This signaling is important during embryonic development. Mutations in this gene can cause pulmonary hypertension. [provided by RefSeq, Mar 2013]