人 PREX1 (NM_020820) cDNA克隆

Accession: NM_020820
基因名称: PREX1
基因别名: P-REX1
基因描述: Homo sapiens phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 (PREX1), mRNA.
种属: Human
CDS区长度: 4980 (查看编码区序列)
翻译后氨基酸长度: 1659 (查看氨基酸序列)
产品编号 产品名称 载体 规格 价格
G170018 人 PREX1 (NM_020820) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene acts as a guanine nucleotide exchange factor for the RHO family of small GTP-binding proteins (RACs). It has been shown to bind to and activate RAC1 by exchanging bound GDP for free GTP. The encoded protein, which is found mainly in the cytoplasm, is activated by phosphatidylinositol-3,4,5-trisphosphate and the beta-gamma subunits of heterotrimeric G proteins. [provided by RefSeq, Jul 2008]