人 MAX (NM_001271069) cDNA克隆

基本信息

Accession: NM_001271069
基因名称: MAX
基因别名: bHLHd4
基因描述: Homo sapiens MYC associated factor X (MAX), transcript variant 8, mRNA.
种属: Human
CDS区长度: 225 (查看编码区序列)
翻译后氨基酸长度: 74 (查看氨基酸序列)
Transcript Variant: This variant (8) lacks two alternate in-frame exons in the coding region and includes an alternate 3' terminal exon, compared to variant 1. It encodes isoform h which is shorter and has a distinct C-terminus, compared to isoform a.

订购信息

产品编号 产品名称 载体 规格 价格
G100093 人 MAX (NM_001271069) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 MAX (NM_002382) cDNA克隆 transcript variant 1
人 MAX (NM_145112) cDNA克隆 transcript variant 2
人 MAX (NM_145113) cDNA克隆 transcript variant 3
人 MAX (NM_145114) cDNA克隆 transcript variant 4
人 MAX (NM_197957) cDNA克隆 transcript variant 6
人 MAX (NM_001271068) cDNA克隆 transcript variant 7
人 MAX (NM_001271069) cDNA克隆 transcript variant 8

基因简介

The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

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