人 RNF7 (NM_001201370) cDNA克隆

基本信息

Accession: NM_001201370
基因名称: RNF7
基因别名: SAG; ROC2; CKBBP1
基因描述: Homo sapiens ring finger protein 7 (RNF7), transcript variant 4, mRNA.
种属: Human
CDS区长度: 294 (查看编码区序列)
翻译后氨基酸长度: 97 (查看氨基酸序列)
Transcript Variant: This variant (4) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (4) has the same N- and C-termini but is shorter compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G100185 人 RNF7 (NM_001201370) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 RNF7 (NM_014245) cDNA克隆 transcript variant 1
人 RNF7 (NM_183237) cDNA克隆 transcript variant 3
人 RNF7 (NM_001201370) cDNA克隆 transcript variant 4

基因简介

The protein encoded by this gene is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1/CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHUK/IKK-alpha/IKBKA) and p27Kip1(CDKN1B). Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

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