人 SDHC (NM_001035511) cDNA克隆

基本信息

Accession: NM_001035511
基因名称: SDHC
基因别名: CYBL; PGL3; QPS1; SDH3; CYB560
基因描述: Homo sapiens succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa (SDHC), transcript variant 2, mRNA.
种属: Human
CDS区长度: 453 (查看编码区序列)
翻译后氨基酸长度: 150 (查看氨基酸序列)
Transcript Variant: This variant (2, also known as delta5) lacks an alternate exon in the 3' coding region, which results in a frameshift, compared to variant 1. The encoded isoform (2) is shorter and has a distinct C-terminus, compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G100343 人 SDHC (NM_001035511) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 SDHC (NM_003001) cDNA克隆 transcript variant 1
人 SDHC (NM_001035511) cDNA克隆 transcript variant 2
人 SDHC (NM_001035512) cDNA克隆 transcript variant 3
人 SDHC (NM_001035513) cDNA克隆 transcript variant 4
人 SDHC (NM_001278172) cDNA克隆 transcript variant 5

基因简介

This gene encodes one of four nuclear-encoded subunits that comprise succinate dehydrogenase, also known as mitochondrial complex II, a key enzyme complex of the tricarboxylic acid cycle and aerobic respiratory chains of mitochondria. The encoded protein is one of two integral membrane proteins that anchor other subunits of the complex, which form the catalytic core, to the inner mitochondrial membrane. There are several related pseudogenes for this gene on different chromosomes. Mutations in this gene have been associated with paragangliomas. Alternatively spliced transcript variants have been described. [provided by RefSeq, May 2013]

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