人 ACOT11 (NM_147161) cDNA克隆

Accession: NM_147161
基因名称: ACOT11
基因别名: BFIT; THEA; THEM1; STARD14
基因描述: Homo sapiens acyl-CoA thioesterase 11 (ACOT11), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1785 (查看编码区序列)
翻译后氨基酸长度: 594 (查看氨基酸序列)
Transcript Variant: This variant (2) uses alternate exons in the 3' coding region and UTR, compared to variant 1. The encoded isoform (BFIT2) has a distinct C-terminus compared to isoform BFIT1.
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G100554 人 ACOT11 (NM_147161) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the acyl-CoA thioesterase family which catalyse the conversion of activated fatty acids to the corresponding non-esterified fatty acid and coenzyme A. Expression of a mouse homolog in brown adipose tissue is induced by low temperatures and repressed by warm temperatures. Higher levels of expression of the mouse homolog has been found in obesity-resistant mice compared with obesity-prone mice, suggesting a role of acyl-CoA thioesterase 11 in obesity. Alternative splicing results in transcript variants. [provided by RefSeq, Nov 2010]