人 SOD2 (NM_000636) cDNA克隆

Accession: NM_000636
基因名称: SOD2
基因别名: IPOB; MNSOD; MVCD6
基因描述: Homo sapiens superoxide dismutase 2, mitochondrial (SOD2), transcript variant 1, mRNA.
种属: Human
CDS区长度: 669 (查看编码区序列)
翻译后氨基酸长度: 222 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (A). Variants 1 and 2 encode the same isoform (A).
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G100563 人 SOD2 (NM_000636) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]