人 WDR4 (NM_001260477) cDNA克隆

基本信息

Accession: NM_001260477
基因名称: WDR4
基因别名: TRM82; TRMT82
基因描述: Homo sapiens WD repeat domain 4 (WDR4), transcript variant 6, mRNA.
种属: Human
CDS区长度: 801 (查看编码区序列)
翻译后氨基酸长度: 266 (查看氨基酸序列)
Transcript Variant: This variant (6) contains an alternate 5' terminal exon and uses an alternate donor splice site at an exon in the 5' region compared to variant 1, resulting in translation initiation from an in-frame downstream AUG and an isoform (3) with a shorter N-terminus compared to isoform 1. Variants 4-6 encode the same isoform.

订购信息

产品编号 产品名称 载体 规格 价格
G100925 人 WDR4 (NM_001260477) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 WDR4 (NM_018669) cDNA克隆 transcript variant 1
人 WDR4 (NM_033661) cDNA克隆 transcript variant 2
人 WDR4 (NM_001260474) cDNA克隆 transcript variant 3
人 WDR4 (NM_001260475) cDNA克隆 transcript variant 4
人 WDR4 (NM_001260476) cDNA克隆 transcript variant 5
人 WDR4 (NM_001260477) cDNA克隆 transcript variant 6

基因简介

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is excluded as a candidate for a form of nonsyndromic deafness (DFNB10), but is still a candidate for other disorders mapped to 21q22.3 as well as for the development of Down syndrome phenotypes. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2012]

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