Mitochondrial DNA encodes 13 proteins that play essential roles in the respiratory chain, while all proteins involved in mitochondrial translation are encoded by nuclear genes that are imported from the cytoplasm. MTRF1L is a nuclear-encoded protein that functions as a releasing factor that recognizes termination codons and releases mitochondrial ribosomes from the synthesized protein (summary by Nozaki et al., 2008 [PubMed 18429816]).[supplied by OMIM, Nov 2010]
人 MTRF1L (NM_001114184) cDNA克隆
| Accession: | NM_001114184 |
|---|---|
| 基因名称: | MTRF1L |
| 基因别名: | MRF1L; HMRF1L; mtRF1a |
| 基因描述: | Homo sapiens mitochondrial translational release factor 1-like (MTRF1L), transcript variant 2, mRNA. |
| 种属: | Human |
| CDS区长度: | 816 (查看编码区序列) |
| 翻译后氨基酸长度: | 271 (查看氨基酸序列) |
| Transcript Variant: | This variant (2) lacks an alternate coding exon compared to variant 1, that causes a frameshift. The resulting isoform (b) has a shorter and distinct C-terminus compared to isoform a. |
| 人 MTRF1L (NM_019041) cDNA克隆 | transcript variant 1 |
| 人 MTRF1L (NM_001114184) cDNA克隆 | transcript variant 2 |
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