The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including NK cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily. [provided by RefSeq, Jul 2008]
人 LAIR1 (NM_021706) cDNA克隆
| Accession: | NM_021706 |
|---|---|
| 基因名称: | LAIR1 |
| 基因别名: | CD305; LAIR-1 |
| 基因描述: | Homo sapiens leukocyte-associated immunoglobulin-like receptor 1 (LAIR1), transcript variant b, mRNA. |
| 种属: | Human |
| CDS区长度: | 813 (查看编码区序列) |
| 翻译后氨基酸长度: | 270 (查看氨基酸序列) |
| Transcript Variant: | This variant (b) lacks an internal exon encoding 17 amino acids; the reading frame is maintained relative to variant a. |
| 人 LAIR1 (NM_002287) cDNA克隆 | transcript variant a |
| 人 LAIR1 (NM_021706) cDNA克隆 | transcript variant b |
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