人 NPM1 (NM_002520) cDNA克隆

Accession: NM_002520
基因名称: NPM1
基因别名: B23; NPM
基因描述: Homo sapiens nucleophosmin (nucleolar phosphoprotein B23, numatrin) (NPM1), transcript variant 1, mRNA.
种属: Human
CDS区长度: 885 (查看编码区序列)
翻译后氨基酸长度: 294 (查看氨基酸序列)
Transcript Variant: This predominant variant (1) represents the longest transcript and encodes the longest isoform (1).
产品编号 产品名称 载体 规格 价格
G101055 人 NPM1 (NM_002520) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Nov 2009]