人 SAE1 (NM_001145713) cDNA克隆

基本信息

Accession: NM_001145713
基因名称: SAE1
基因别名: AOS1; SUA1; UBLE1A; HSPC140
基因描述: Homo sapiens SUMO1 activating enzyme subunit 1 (SAE1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 900 (查看编码区序列)
翻译后氨基酸长度: 299 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks two alternate exons, compared to variant 1, which causes a frameshift. The resulting protein (isoform b) has a distinct C-terminus and is shorter than isoform a.

订购信息

产品编号 产品名称 载体 规格 价格
G101281 人 SAE1 (NM_001145713) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 SAE1 (NM_005500) cDNA克隆 transcript variant 1
人 SAE1 (NM_016402) cDNA克隆 transcript variant 1
人 SAE1 (NM_001145713) cDNA克隆 transcript variant 2
人 SAE1 (NM_001145714) cDNA克隆 transcript variant 3

基因简介

Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2 (MIM 613295) form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]).[supplied by OMIM, Mar 2010]

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