LCMT1 catalyzes the methylation of the carboxyl group of the C-terminal leucine residue (leu309) of the catalytic subunit of protein phosphatase-2A (PPP2CA; MIM 176915) (De Baere et al., 1999 [PubMed 10600115]).[supplied by OMIM, Mar 2008]
Accession: | NM_001032391 |
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基因名称: | LCMT1 |
基因别名: | LCMT; PPMT1; CGI-68 |
基因描述: | Homo sapiens leucine carboxyl methyltransferase 1 (LCMT1), transcript variant 2, mRNA. |
种属: | Human |
CDS区长度: | 840 (查看编码区序列) |
翻译后氨基酸长度: | 279 (查看氨基酸序列) |
Transcript Variant: | This variant (2) lacks two alternate internal exons that encode an in-frame segment, compared to variant 1. The resulting isoform (b) is shorter than isoform a. |
人 LCMT1 (NM_016309) cDNA克隆 | transcript variant 1 |
人 LCMT1 (NM_001032391) cDNA克隆 | transcript variant 2 |
LCMT1 catalyzes the methylation of the carboxyl group of the C-terminal leucine residue (leu309) of the catalytic subunit of protein phosphatase-2A (PPP2CA; MIM 176915) (De Baere et al., 1999 [PubMed 10600115]).[supplied by OMIM, Mar 2008]