人 DCN (NM_133505) cDNA克隆

Accession: NM_133505
基因名称: DCN
基因别名: CSCD; PG40; PGII; PGS2; DSPG2; SLRR1B
基因描述: Homo sapiens decorin (DCN), transcript variant C, mRNA.
种属: Human
CDS区长度: 639 (查看编码区序列)
翻译后氨基酸长度: 212 (查看氨基酸序列)
Transcript Variant: This variant (C) lacks exons 3, 4 and 5 in the coding region compared to variant A1. This causes an internal frameshift and the encoded isoform c is 147 amino acids shorter compared to isoform a. Thus it is not clear if cleavage takes place for the mature peptide to be produced from the proprotein.
产品编号 产品名称 载体 规格 价格
G101383 人 DCN (NM_133505) cDNA克隆 pDONR223 2ug质粒 点击询价
人 DCN (NM_001920) cDNA克隆 transcript variant A1
人 DCN (NM_133503) cDNA克隆 transcript variant A2
人 DCN (NM_133504) cDNA克隆 transcript variant B
人 DCN (NM_133505) cDNA克隆 transcript variant C
人 DCN (NM_133506) cDNA克隆 transcript variant D
人 DCN (NM_133507) cDNA克隆 transcript variant E

The protein encoded by this gene is a small cellular or pericellular matrix proteoglycan that is closely related in structure to biglycan protein. The encoded protein and biglycan are thought to be the result of a gene duplication. This protein is a component of connective tissue, binds to type I collagen fibrils, and plays a role in matrix assembly. It contains one attached glycosaminoglycan chain. This protein is capable of suppressing the growth of various tumor cell lines. There are multiple alternatively spliced transcript variants known for this gene. This gene is a candidate gene for Marfan syndrome. [provided by RefSeq, Jul 2008]