人 MAEA (NM_001017405) cDNA克隆

Accession: NM_001017405
基因名称: MAEA
基因别名: EMP; EMLP; GID9; PIG5; HLC-10
基因描述: Homo sapiens macrophage erythroblast attacher (MAEA), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1191 (查看编码区序列)
翻译后氨基酸长度: 396 (查看氨基酸序列)
Transcript Variant: This variant (1) is the longer transcript and encodes the longer isoform (1).
产品编号 产品名称 载体 规格 价格
G101555 人 MAEA (NM_001017405) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene product mediates the attachment of erythroblasts to macrophages. This attachment promotes terminal maturation and enucleation of erythroblasts, presumably by suppressing apoptosis. This protein is an integral membrane protein with the N-terminus on the extracellular side and the C-terminus on the cytoplasmic side of the cell. Two immunologically related isoforms of erythroblast macrophage protein with apparent molecular weights of 33 kD and 36 kD were detected in macrophage membranes; this gene encodes the larger isoform. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008]