人 NDRG1 (NM_001258433) cDNA克隆

基本信息

Accession: NM_001258433
基因名称: NDRG1
基因别名: GC4; RTP; DRG1; NDR1; NMSL; TDD5; CAP43; CMT4D; DRG-1; HMSNL; RIT42; TARG1; PROXY1
基因描述: Homo sapiens N-myc downstream regulated 1 (NDRG1), transcript variant 4, mRNA.
种属: Human
CDS区长度: 942 (查看编码区序列)
翻译后氨基酸长度: 313 (查看氨基酸序列)
Transcript Variant: This variant (4) lacks an internal exon and initiates translation at a downstream, in-frame start codon, compared to variant 1. The encoded isoform (3) has a shorter N-terminus, compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G101634 人 NDRG1 (NM_001258433) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 NDRG1 (NM_001135242) cDNA克隆 transcript variant 1
人 NDRG1 (NM_006096) cDNA克隆 transcript variant 2
人 NDRG1 (NM_001258432) cDNA克隆 transcript variant 3
人 NDRG1 (NM_001258433) cDNA克隆 transcript variant 4

基因简介

This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. The encoded protein is necessary for p53-mediated caspase activation and apoptosis. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4D, and expression of this gene may be a prognostic indicator for several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]

相关产品