人 GAK (NM_005255) cDNA克隆

Accession: NM_005255
基因名称: GAK
基因别名: DNAJ26; DNAJC26
基因描述: Homo sapiens cyclin G associated kinase (GAK), transcript variant 1, mRNA.
种属: Human
CDS区长度: 3936 (查看编码区序列)
翻译后氨基酸长度: 1311 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
产品编号 产品名称 载体 规格 价格
G101752 人 GAK (NM_005255) cDNA克隆 pDONR223 2ug质粒 点击询价

In all eukaryotes, the cell cycle is governed by cyclin-dependent protein kinases (CDKs), whose activities are regulated by cyclins and CDK inhibitors in a diverse array of mechanisms that involve the control of phosphorylation and dephosphorylation of Ser, Thr or Tyr residues. Cyclins are molecules that possess a consensus domain called the 'cyclin box.' In mammalian cells, 9 cyclin species have been identified, and they are referred to as cyclins A through I. Cyclin G is a direct transcriptional target of the p53 tumor suppressor gene product and thus functions downstream of p53. GAK is an association partner of cyclin G and CDK5. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]