人 SH2B1 (NM_001145812) cDNA克隆

基本信息

Accession: NM_001145812
基因名称: SH2B1
基因别名: PSM; SH2B
基因描述: Homo sapiens SH2B adaptor protein 1 (SH2B1), transcript variant 3, mRNA.
种属: Human
CDS区长度: 2016 (查看编码区序列)
翻译后氨基酸长度: 671 (查看氨基酸序列)
Transcript Variant: This variant (3) differs in the 5' UTR and contains an alternate exon in the 3' coding region, which results in a frameshift and an early stop codon compared to variant 1. The resulting protein (isoform 2), also known as SH2B adaptor protein 1 beta, is shorter and has a distinct C-terminus compared to isoform 1. Variants 2, 3 and 4 encode the same protein.

订购信息

产品编号 产品名称 载体 规格 价格
G101843 人 SH2B1 (NM_001145812) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 SH2B1 (NM_001145795) cDNA克隆 transcript variant 1
人 SH2B1 (NM_015503) cDNA克隆 transcript variant 2
人 SH2B1 (NM_001145812) cDNA克隆 transcript variant 3
人 SH2B1 (NM_001145796) cDNA克隆 transcript variant 4
人 SH2B1 (NM_001145797) cDNA克隆 transcript variant 5

基因简介

This gene encodes a member of the SH2-domain containing mediators family. The encoded protein mediates activation of various kinases and may function in cytokine and growth factor receptor signaling and cellular transformation. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2009]

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