人 SEPT6 (NM_145799) cDNA克隆

Accession: NM_145799
基因名称: SEPT6
基因别名: SEP2; SEPT2; RP5-876A24.2
基因描述: Homo sapiens septin 6 (SEPT6), transcript variant I, mRNA.
种属: Human
CDS区长度: 1284 (查看编码区序列)
翻译后氨基酸长度: 427 (查看氨基酸序列)
Transcript Variant: This variant (I) contains an additional segment in the 3' coding region, which leads to a frameshift and immediate translation termination, as compared to variant II. The resulting isoform (A) is truncated at the C-terminus, as compared to isoform B.
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G101858 人 SEPT6 (NM_145799) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins. This gene encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identified, but its biological validity has not been determined. [provided by RefSeq, Jul 2008]