人 SUFU (NM_016169) cDNA克隆

Accession: NM_016169
基因名称: SUFU
基因别名: SUFUH; SUFUXL; PRO1280
基因描述: Homo sapiens suppressor of fused homolog (Drosophila) (SUFU), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1455 (查看编码区序列)
翻译后氨基酸长度: 484 (查看氨基酸序列)
Transcript Variant: Transcript Variant: This variant (1) encodes the longer isoform (1).
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G102135 人 SUFU (NM_016169) cDNA克隆 pDONR223 2ug质粒 点击询价

The Hedgehog signaling pathway plays an important role in early human development. The pathway is a signaling cascade that plays a role in pattern formation and cellular proliferation during development. This gene encodes a negative regulator of the hedgehog signaling pathway. Defects in this gene are a cause of medulloblastoma. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]