人 DUS2 (NM_001271763) cDNA克隆

Accession: NM_001271763
基因名称: DUS2
基因别名: SMM1; DUS2L; URLC8
基因描述: Homo sapiens dihydrouridine synthase 2 (DUS2), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1377 (查看编码区序列)
翻译后氨基酸长度: 458 (查看氨基酸序列)
Transcript Variant: This variant (3) lacks two alternate exons, resulting in the loss of an in-frame segment in the coding region, compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
产品编号 产品名称 载体 规格 价格
G102160 人 DUS2 (NM_001271763) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a cytoplasmic protein that catalyzes the conversion of uridine residues to dihydrouridine in the D-loop of tRNA. The resulting modified bases confer enhanced regional flexibility to tRNA. The encoded protein may increase the rate of translation by inhibiting an interferon-induced protein kinase. This gene has been implicated in pulmonary carcinogenesis. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Nov 2012]