人 CHRNA3 (NM_000743) cDNA克隆

Accession: NM_000743
基因名称: CHRNA3
基因别名: LNCR2; PAOD2; NACHRA3
基因描述: Homo sapiens cholinergic receptor, nicotinic, alpha 3 (neuronal) (CHRNA3), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1518 (查看编码区序列)
翻译后氨基酸长度: 505 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
产品编号 产品名称 载体 规格 价格
G102180 人 CHRNA3 (NM_000743) cDNA克隆 pDONR223 2ug质粒 点击询价

This locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2009]