人 FASTK (NM_033015) cDNA克隆

基本信息

Accession: NM_033015
基因名称: FASTK
基因别名: FAST
基因描述: Homo sapiens Fas-activated serine/threonine kinase (FASTK), transcript variant 4, mRNA.
种属: Human
CDS区长度: 1227 (查看编码区序列)
翻译后氨基酸长度: 408 (查看氨基酸序列)
Transcript Variant: This variant (4) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (4) has the same N- and C-termini but is shorter compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G102260 人 FASTK (NM_033015) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 FASTK (NM_006712) cDNA克隆 transcript variant 1
人 FASTK (NM_033015) cDNA克隆 transcript variant 4
人 FASTK (NM_001258461) cDNA克隆 transcript variant 5

基因简介

The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined. [provided by RefSeq, Jul 2008]

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