人 DIDO1 (NM_080797) cDNA克隆

Accession: NM_080797
基因名称: DIDO1
基因别名: BYE1; DIO1; DATF1; DIDO2; DIDO3; DIO-1; DATF-1; C20orf158; dJ885L7.8
基因描述: Homo sapiens death inducer-obliterator 1 (DIDO1), transcript variant 3, mRNA.
种属: Human
CDS区长度: 3570 (查看编码区序列)
翻译后氨基酸长度: 1189 (查看氨基酸序列)
Transcript Variant: This variant (3) contains a different terminal exon, compared to variant 4. It encodes a protein (isoform b) that has a distinct and shorter C-terminus when it is compared to isoform c. Variants 3 and 6 encode the same protein (isoform c).
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G102283 人 DIDO1 (NM_080797) cDNA克隆 pDONR223 2ug质粒 点击询价

Apoptosis, a major form of cell death, is an efficient mechanism for eliminating unwanted cells and is of central importance for development and homeostasis in metazoan animals. In mice, the death inducer-obliterator-1 gene is upregulated by apoptotic signals and encodes a cytoplasmic protein that translocates to the nucleus upon apoptotic signal activation. When overexpressed, the mouse protein induced apoptosis in cell lines growing in vitro. This gene is similar to the mouse gene and therefore is thought to be involved in apoptosis. Alternatively spliced transcripts have been found for this gene, encoding multiple isoforms. [provided by RefSeq, Jul 2008]