人 OS9 (NM_001261423) cDNA克隆

Accession: NM_001261423
基因名称: OS9
基因别名: OS-9; ERLEC2
基因描述: Homo sapiens osteosarcoma amplified 9, endoplasmic reticulum lectin (OS9), transcript variant 8, mRNA.
种属: Human
CDS区长度: 1617 (查看编码区序列)
翻译后氨基酸长度: 538 (查看氨基酸序列)
Transcript Variant: This variant (8) lacks an exon in the 5' coding region and an exon in the 3' coding region, compared to variant 1. The resulting isoform (8) lacks two internal segments, compared to isoform 1.
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G102349 人 OS9 (NM_001261423) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a protein that is highly expressed in osteosarcomas. This protein binds to the hypoxia-inducible factor 1 (HIF-1), a key regulator of the hypoxic response and angiogenesis, and promotes the degradation of one of its subunits. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]